Pioglitazone Reduces Atherogenic Index of Plasma in Patients with Type 2 Diabetes
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چکیده
منابع مشابه
Pioglitazone reduces atherogenic index of plasma in patients with type 2 diabetes.
BACKGROUND Insulin resistance is often associated with increased triglyceride (TG) and decreased HDL-cholesterol (HDL-C) concentrations and increased small LDL particles. The Atherogenic Index of Plasma (AIP), defined as log(TG/HDL-C), has recently been proposed as a marker of plasma atherogenicity because it is increased in people at higher risk for coronary heart disease and is inversely corr...
متن کاملPioglitazone reduces atherogenic outcomes in type 2 diabetic patients.
AIM The aim of this study was to evaluate the anti-atherogenic outcomes of pioglitazone, a thiazolidinedione derivative, in type 2 diabetic patients. METHODS Eight patients with poor diabetic control were treated with 15 mg of pioglitazone for 4 months. Blood samples were collected monthly, and the levels of fasting plasma glucose (FPG), HbA1c, and lipids, such as triglycerides, total cholest...
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The effect of pioglitazone on splanchnic glucose uptake (SGU), endogenous glucose production (EGP), and hepatic fat content was studied in 14 type 2 diabetic patients (age 50 +/- 2 years, BMI 29.4 +/- 1.1 kg/m(2), HbA(1c) 7.8 +/- 0.4%). Hepatic fat content (magnetic resonance spectroscopy) and SGU (oral glucose load- insulin clamp technique) were quantitated before and after pioglitazone (45 mg...
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Objective: We sought to determine whether dysregulation of arginine metabolism is related to insulin resistance and underlies impaired nitric oxide generation in type 2 diabetic (T2DM) patients. Research Design and Methods: We measured plasma arginase activity, arginine metabolites and skeletal muscle NOS activity in 12 T2DM and 10 age/BMI matched non-diabetic subjects before and following 4 ho...
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Background Diabetes mellitus has many complications; hypoglycemia is one of them that is associated with severe signs and symptoms such as anxiety, psychosocial problems, and poor metabolic control. Objective This study aimed to investigate the factors affecting hypoglycemia fear in patients with type 2 diabetes. Methods The present descriptive-analytic study was conducted on 360 patients wit...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2004
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2004.031757