Pioglitazone Reduces Atherogenic Index of Plasma in Patients with Type 2 Diabetes

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Pioglitazone reduces atherogenic index of plasma in patients with type 2 diabetes.

BACKGROUND Insulin resistance is often associated with increased triglyceride (TG) and decreased HDL-cholesterol (HDL-C) concentrations and increased small LDL particles. The Atherogenic Index of Plasma (AIP), defined as log(TG/HDL-C), has recently been proposed as a marker of plasma atherogenicity because it is increased in people at higher risk for coronary heart disease and is inversely corr...

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Pioglitazone reduces atherogenic outcomes in type 2 diabetic patients.

AIM The aim of this study was to evaluate the anti-atherogenic outcomes of pioglitazone, a thiazolidinedione derivative, in type 2 diabetic patients. METHODS Eight patients with poor diabetic control were treated with 15 mg of pioglitazone for 4 months. Blood samples were collected monthly, and the levels of fasting plasma glucose (FPG), HbA1c, and lipids, such as triglycerides, total cholest...

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Pioglitazone reduces hepatic fat content and augments splanchnic glucose uptake in patients with type 2 diabetes.

The effect of pioglitazone on splanchnic glucose uptake (SGU), endogenous glucose production (EGP), and hepatic fat content was studied in 14 type 2 diabetic patients (age 50 +/- 2 years, BMI 29.4 +/- 1.1 kg/m(2), HbA(1c) 7.8 +/- 0.4%). Hepatic fat content (magnetic resonance spectroscopy) and SGU (oral glucose load- insulin clamp technique) were quantitated before and after pioglitazone (45 mg...

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Insulin Reduces Plasma Arginase Activity in Type 2 Diabetes Patients

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Factors Affecting Hypoglycemia Fear in Patients With Type 2 Diabetes

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 2004

ISSN: 0009-9147,1530-8561

DOI: 10.1373/clinchem.2004.031757